What's the most user friendly but also cost friendly POS software for a small retail business?

What's the most user friendly but also cost friendly POS software for a small retail business?
There's many, many POS systems for small businesses. But two that come to mind are Microsoft's POS which works on a variety of hardware.

Also, Quickbooks Point of Sale very easy to use.

I would suggest checking out these systems!

Ramon Ray, Smallbiztechnology.com
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