9781588294579
Apoptosis and cancer; methods and protocols.
Ed. by Gil Mor and Ayesha B. Alvero.
Humana Press Inc.
2008
266 pages
$99.50
Hardcover
Methods in molecular biology; 414
RC268
The failure of apoptosis--programmed cell death--has long been
implicated in the onset of cancer, but recently it has also been
associated more specifically with the acquisition of resistance to
chemotherapy and immune effectors. Biological scientists, many
describing instruments made by the companies they work for, detail
contemporary techniques for studying the biology of apoptosis and its
role in cancer and resistance. Among the aspects they discuss are the
modulation of apoptosis to reverse chemo-resistance, assessing the
expression of apoptotic markers using large cohort tissue microarrays,
and caspase activity assays.
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