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Internal Medicine News

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Fasting insulin model helps identify prediabetes.(Endocrinology)(Clinical report)
BOSTON -- Prediabetes can be accurately and easily identified in the clinical setting using a predictive model based on fasting insulin quartiles, a study has shown. Given its clinical utility, . . .

Study confirms safety of diclofenac gel for actinic keratosis.(Dermatology)
AMSTERDAM -- Diclofenac 3% gel was well tolerated and showed an excellent safety profile for treatment of multiple actinic keratoses in a primary care postmarketing safety surveillance study. The . . .

Seven common myths about cancer debunked.(Dermatology)
ZURICH -- Recent advances in cancer genetics have fueled the push for targeted therapeutics--and are standing the field of oncology on its head, Dr. Levi A. Garraway said at the annual meeting of . . .

Genes tied to methotrexate response.(Dermatology)
ZURICH -- The goal of individualized methotrexate therapy for psoriasis has drawn a big step closer as a consequence of a large pharmacogenetic study that identified polymorphisms in key genes in . . .

Pregnancy registries.(DRUGS, PREGNANCY, AND LACTATION)
Pregnancy registries are valuable sources of information, and for many drugs and vaccines they are the primary source of human pregnancy experience. The strengths of these registries are their . . .

Prior GDM? Treat without screening.(Women's Health)(gestational diabetes mellitus)
AMSTERDAM -- Seeing and presumptively treating all women with previous gestational diabetes mellitus for GDM early in their subsequent pregnancies--without rescreening them--is likely to improve . . .

Contraceptive ring beats patch in trial.(Women's Health)
MINNEAPOLIS -- Women who are content with combined oral contraceptives but are willing to try a nondaily method of birth control are more likely to be satisfied with the contraceptive ring than . . .

Risk of urinary incontinence rises after hysterectomy.(Women's Health)
Women who undergo hysterectomy for benign indications are more than twice as likely to develop stress urinary incontinence requiring surgery, according to data from a large cohort study. Dr. . . .

Ablation, hysterectomy short-term results similar.(Women's Health)
SAN DIEGO -- Both hysterectomy and endometrial ablation were highly effective short-term treatments for dysfunctional uterine bleeding in a randomized, multi-center trial, but about one-third of . . .

Hysterectomy increases risk of prolapse surgery.(Women's Health)
HOLLYWOOD, FLA. -- Hysterectomy, regardless of surgical approach, increases the risk of future pelvic organ prolapse surgery. In addition, risk is greatest within the first 5 postoperative years, . . .

'Dear Doctor' warning issued on risks of buccal fentanyl.(Neurology)
The manufacturer of the buccal formulation of fentanyl is notifying health care professionals about serious adverse events, including deaths, that have been reported in patients treated with the . . .

Methadone-related emergency visits and deaths on the rise.(Neurology)
SAN FRANCISCO -- The increasing use of methadone for pain management has been shadowed by steep increases in the number of emergency department visits and deaths associated with the drug, according . . .

Patients on chronic opioids can be safe drivers.(Neurology)
SAN FRANCISCO -- On driving simulators, 51 patients on chronic opioids performed just as well as 49 control subjects, preliminary data from an ongoing study found. The conventional recommendation . . .

Vitamins to prevent cognitive decline.(MINDFUL PRACTICE)
The Problem A well-nourished, ambulatory 62-year-old man presents for a general medical exam. He has a history of coronary artery disease and hypertension. He tells you that he has been reading . . .

Coping with dementia booklet.(Neurology)
A 12-page booklet called "What Happens Next?" is designed to answer patients' questions about early-stage dementia. The authors themselves are patients with early-stage dementia who wanted to . . .

Early-onset Alzheimer's gets name change.(Neurology)
CHICAGO -- The increasing incidence of early-onset dementia represents both a national challenge and a future crisis, according to the Alzheimer's Association, which is about to change . . .

Courageous analysis.(LETTERS)(Letter to the editor)
I was pleased to read the analysis by Dr. Jamshid A. Marvasti ("Physicians as Terrorists," Guest Editorial, Sept. 1, 2007, p. 9). At a time when much of our discourse is based on depictions . . .

Even physicians can be sociopaths.(LETTERS)(Letter to the editor)
Dr. Jamshid A. Marvasti explains to us why some doctors become suicidal, homicidal killers ("Physicians as Terrorists," Guest Editorial, Sept. 1, 2007, p. 9). He gives the example of Iraqi doctor . . .

Be clear on 'life' and 'death'.(LETTERS)(Letter to the editor)
Thank you for publishing the interesting exchange between Dr. Robert Sade and Dr. Michael A. Grodin on organ donation after cardiac arrest--misnamed "cardiac death" in the article ("Should organ . . .

Patients contribute to errors.(LETTERS)(Letter to the editor)
As an endocrinologist, I deeply admire the gumption of internists who soldier on despite all the cards stacked against them in the current medical practice world. As such I was both disturbed and . . .

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