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Inspection Monitor

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Device manufacturer cited for CAPAs and MDRs in 11-item 483.(MEDICAL DEVICES)
Advanced Imaging Research, Cleveland, OH, Cincinnati, OH, District Advanced Imaging Research, Cleveland, OH, was the recipient of an 11-item 483 in a 2006 inspection due to improper CAPA . . .

Vi Jon Labs gets two 483s for written procedures, improper calibration.(HUMAN DRUGS)
Vi Jon Laboratories, St. Louis, MO, Lenexa, KS, District Two FDA inspections of Vi Jon Laboratories, St. Louis, MO, revealed a lack of written procedures for production and process controls, . . .

Kutol Products receives 4-item write-up for failure to reject non-conforming batches.(HUMAN DRUGS)
Kutol Products, Cincinnati, OH, Cincinnati District Kutol Products, Cincinnati, OH, was hit with a four-item 483 for failure to reject batches of hand sanitizer that did not meet . . .

FDA's new CMC review process aims to foster more efficient, science-based control of product quality.
PHILADELPHIA -- FDA's new systems-based approach to chemistry, manufacturing and control (CMC) review promises to be one in which companies that demonstrate adequate process knowledge and control . . .

Inspection log.
The following is a partial list of inspection documents that have been requested under the Freedom of Information Act by various parties, according to FDA's Freedom of Information (FOI) Log, . . .

BioLife Plasma cleared of wrongdoing in donor fatality involving 42 year-old male.(BIOLOGICS)
BioLife Plasma Services, Ruston, LA, Center for Biologics A CBER-directed inspection was conducted on BioLife Plasma Services, Ruston, LA, because of a donor fatality that occurred on Dec. 9, . . .

Pharmaceutical Specialties passes FDA audit; Part 11 mentioned in EIR.(HUMAN DRUGS)
Pharmaceutical Specialties, Rochester, MN, Minneapolis District No 483 was issued in an inspection of Pharmaceutical Specialties, Rochester, MN. However, several observations were noted regarding . . .

Cassidy slapped with 7-item 483 in 1st inspection; 1-item 483 in 2nd.(HUMAN DRUGS)
Cassidy, St. Paul, MN, Minneapolis District St. Paul, MN-based cosmetic manufacturer Cassidy received a seven-item 483 for lack of stability testing and employee training, among other violations. . . .

Cosmetics manufacturer cited for packaging issues and unsanitary practices.(HUMAN DRUGS)
Aveda, Minneapolis, Minneapolis District A 483 was not issued following an FDA audit of cosmetics manufacturer Aveda in Minneapolis, but the agency noted the firm produced a breath freshener that . . .

Ameri-Pac written up by agency for contaminated equipment and lack of cleaning records.(HUMAN DRUGS)
Ameri-Pac, St. Joseph, MO, Lenexa, KS, District Ameri-Pac, an animal nutritional supplement manufacturer based in Saint Joseph, MO, received an 11-item 483 because its equipment and utensils were . . .

9-item 483 to Alwyn for lack of validation procedures and poor laboratory controls.(HUMAN DRUGS)
Alwyn, Lake Crystal, MN, Minneapolis District Alwyn, an OTC drugs and cosmetics manufacturer in Lake Crystal, MN, was hit with a nine-item 483 because control procedures were not established that . . .

FDA moving ahead with TSE rule, despite 'theoretical' risk from blood, plasma products.
Despite noting there is just a "theoretical risk" from blood and plasma products, FDA can be expected within the year to issue proposed rules regarding minimizing the risk of new variant . . .

Inspection log.
The following is a partial list of inspection documents that have been requested under the Freedom of Information Act by various parties, according to FDA's Freedom of Infor-mation (FOI) Log, . . .

Device firm passes audit; more documentation needed on complaints.(MEDICAL DEVICES)
American Medical Systems, Minnetonka, MN, Minneapolis District American Medical Systems (AMS), Minnetonka, MN, was not cited in a recent QSIT inspection by investigator Jocelyn Muggli from . . .

Tyco receives clean report from agency.(HUMAN DRUGS)
Tyco Healthcare, St. Louis, MO, Kansas City District A recent GMP inspection covering the manufacturing operations of methylphenidate hydrochloride USP, produced by Tyco Healthcare, St. Louis, . . .

I Shay passes inspection with no observations noted.(HUMAN DRUGS)
I Shay Cosmetics, Hawthorne, CA, Irvine, CA, District No 483 observations were noted in an initial inspection of I Shay Cosmetics, Hawthorne, CA, but investigator John Gonzalez from the Irvine, . . .

Classic Cosmetics cited for lack of process and cleaning validation in 4-item 483.(HUMAN DRUGS)
Classic Cosmetics, Chatsworth, CA, Irvine, CA, District Classic Cosmetics, Chatsworth, CA, a contract manufacturer of cosmetics and OTC drug products, received a four-item 483 for lack of process . . .

Cima Labs receives 3-item 483, but gets okay in follow-up inspection.(HUMAN DRUGS)
Cima Laboratories, Brooklyn Park, MN, Minneapolis District An inspection of Cima Laboratories, Brooklyn Park, MN, netted the prescription and OTC drug manufacturer a three-item 483 for . . .

Central Admixture slapped with 2-item 483 cited for faulty microbiological tests.(HUMAN DRUGS)
Central Admixture Pharmacy Services, Santa Fe Springs, CA, San Diego, Irvine, CA, District An unannounced GMP inspection of Central Admixture Pharmacy Services, Santa Fe Springs, CA, revealed . . .

SOPs on production, process controls top 483 citations for drugs in '05.
ATHENS, GA -- "Written production and process control procedures not followed" was the No. 1 violation cited on 483s issued to drug manufacturers in fiscal 2005, followed by other SOP issues. . . .

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