You can be on Entrepreneur’s cover!

Dow Rockets 1,434 points to Record High As Pfizer Says Covid-19 Vaccine Shows Stunning Effectiveness While cyclical stocks in the airline, restaurant, and financial sectors soared, popular work-from-home names like Zoom, Peloton, and Netflix plummeted.

entrepreneur daily
Xinhua News Agency | Getty Images

Covid-19 vaccine progress on Monday appeared to be what the stock market needed to hit new highs. Both the S&P 500 and the Dow Jones industrial average opened at intraday records after Pfizer and BioNTech announced that their COVID-19 vaccine was found to be more than 90% effective in preventing the illness during its phase-three trial, setting it up for an emergency rollout.

The drugmakers said no serious safety concerns had been observed throughout the trial, which enrolled about 44,000 patients.

Pfizer and BioNTech are now ramping up production of the vaccine. They said they expected to produce more than 50 million doses by the end of the year and more than 1 billion doses in 2021.

Here's where U.S. indexes stood shortly after the 9:30 a.m. ET open on Monday:

The vaccine-progress news rippled through various areas of the stock market. Pfizer soared 8% as investors expect the company to benefit from a swift rollout of the vaccine.

The cyclical reopening trade also fueled gains on Monday morning. Airline and cruise-line stocks surged, as investors likely anticipate pent-up demand for travel once a vaccine has been widely administered. AMC Entertainment Holdings led a broad rally in movie-theater stocks, spiking roughly 48% on Monday morning.

Berkshire Hathaway soared 7% on stock purchases, record buybacks, and the Pfizer vaccine news.

On the flip side, work-from-home stocks suffered on the news, as people are more likely to spend less time at home and get back to offices once the Covid-19 pandemic is in the rearview mirror. Zoom, Peloton, DocuSign, and Netflix cratered on Monday.

Biogen plummeted 32% after a Food and Drug Administration advisory committee signaled that its Alzheimer's therapy would not receive approval early next year.

Oil prices soared. West Texas Intermediate crude climbed as much as 11%, to $41.33 per barrel. Brent crude, oil's international benchmark, jumped 10%, to $43.48 per barrel, at intraday highs.

Gold slid on Monday, falling as much as 4.2, to $1,868.97 per ounce.

Want to be an Entrepreneur Leadership Network contributor? Apply now to join.

Editor's Pick

Side Hustle

This Flexible Side Hustle Is Helping Millions Earn Extra Cash — and Might Be 'More Attractive' Than an Office Job

Side hustles remain popular for additional income — and have many questioning the 9-5 model altogether.

Marketing

A Step-by-Step Guide on How to Make Money With Facebook Ads, According to Experts

Creating the right message is a crucial first step to making money with Facebook ads, but it doesn't end there. This guide will help you create ads that actually convert.

Business Ideas

63 Small Business Ideas to Start in 2024

We put together a list of the best, most profitable small business ideas for entrepreneurs to pursue in 2024.

Business News

A Surprising Number of U.S. Couples Have Secret Financial Accounts, According to a New Survey — And Most Have Not Talked About a Key Retirement Question

Two in five Gen X and young Boomer couples surveyed do not have a financial plan in place for retiring together.

Business Models

Why the Coaching Industry Is Poised for Transformative Growth in the Gig Economy Era — and How to Navigate the Waves of Change

This article highlights five trends shaping the coaching industry and offers insights into how entrepreneurs can adapt and thrive in this evolving landscape.