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Should You Invest in the iShares Biotechnology ETF (IBB)?

Sector ETF report for IBB

This story originally appeared on Zacks

Designed to provide broad exposure to the Healthcare - Biotech segment of the equity market, the iShares Biotechnology ETF (IBB) is a passively managed exchange traded fund launched on 02/05/2001.

- Zacks

Passively managed ETFs are becoming increasingly popular with institutional as well as retail investors due to their low cost, transparency, flexibility and tax efficiency. They are excellent vehicles for long term investors.

Investor-friendly, sector ETFs provide many options to gain low risk and diversified exposure to a broad group of companies in particular sectors. Healthcare - Biotech is one of the 16 broad Zacks sectors within the Zacks Industry classification. It is currently ranked 11, placing it in bottom 31%.

Index Details

The fund is sponsored by Blackrock. It has amassed assets over $10.14 billion, making it one of the largest ETFs attempting to match the performance of the Healthcare - Biotech segment of the equity market. IBB seeks to match the performance of the Nasdaq Biotechnology Index before fees and expenses.

The ICE Biotechnology Index contains securities of NASDAQ listed companies that are classified as either biotechnology or pharmaceuticals.


Cost is an important factor in selecting the right ETF, and cheaper funds can significantly outperform their more expensive counterparts if all other fundamentals are the same.

Annual operating expenses for this ETF are 0.45%, making it on par with most peer products in the space.

It has a 12-month trailing dividend yield of 0.21%.

Sector Exposure and Top Holdings

While ETFs offer diversified exposure, which minimizes single stock risk, a deep look into a fund's holdings is a valuable exercise. And, most ETFs are very transparent products that disclose their holdings on a daily basis.

This ETF has heaviest allocation in the Healthcare sector--about 99.90% of the portfolio.

Looking at individual holdings, Amgen Inc (AMGN) accounts for about 7.95% of total assets, followed by Moderna Inc (MRNA) and Gilead Sciences Inc (GILD).

The top 10 holdings account for about 47.89% of total assets under management.

Performance and Risk

The ETF return is roughly 2.39% so far this year and was up about 1.05% in the last one year (as of 12/31/2021). In that past 52-week period, it has traded between $145.27 and $176.21.

The ETF has a beta of 0.87 and standard deviation of 25.63% for the trailing three-year period, making it a high risk choice in the space. With about 270 holdings, it effectively diversifies company-specific risk.


IShares Biotechnology ETF holds a Zacks ETF Rank of 1 (Strong Buy), which is based on expected asset class return, expense ratio, and momentum, among other factors. Because of this, IBB is an excellent option for investors seeking exposure to the Health Care ETFs segment of the market. There are other additional ETFs in the space that investors could consider as well.

First Trust NYSE Arca Biotechnology ETF (FBT) tracks NYSE Arca Biotechnology Index and the SPDR S&P Biotech ETF (XBI) tracks S&P Biotechnology Select Industry Index. First Trust NYSE Arca Biotechnology ETF has $1.72 billion in assets, SPDR S&P Biotech ETF has $7.26 billion. FBT has an expense ratio of 0.55% and XBI charges 0.35%.

Bottom Line

To learn more about this product and other ETFs, screen for products that match your investment objectives and read articles on latest developments in the ETF investing universe, please visit Zacks ETF Center.

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iShares Biotechnology ETF (IBB): ETF Research Reports


Amgen Inc. (AMGN): Free Stock Analysis Report


Gilead Sciences, Inc. (GILD): Free Stock Analysis Report


Moderna, Inc. (MRNA): Free Stock Analysis Report


SPDR S&P Biotech ETF (XBI): ETF Research Reports


First Trust NYSE Arca Biotechnology ETF (FBT): ETF Research Reports


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Zacks Investment Research