This is a subscriber-only article. Join Entrepreneur+ today for access

Learn More

Already have an account?

Sign in
Entrepreneur Plus - Short White
For Subscribers

Innovation Nation 50 cities and 10 lifestyles energizing businesses of all shapes and sizes.

By Jason Ankeny

Opinions expressed by Entrepreneur contributors are their own.

Whatever your entrepreneurial aspirations, there's a city to match your needs, accelerate your company's growth and improve your quality of life. Which is the one for you? Entrepreneur identifies 50 cities and 10 lifestyles energizing businesses of all shapes and sizes.

Even in harsh economic times, America is still the land of opportunity, especially for entrepreneurs with the vision, ambition and flexibility to follow that opportunity wherever it may lead. In an increasingly connected world, no longer are businesses or their owners tethered to one spot on the map: Whether you're sizing up a regional opportunity, looking for a change of scenery or simply desiring a certain lifestyle, there's a location and culture that's perfect for you.

The challenge is identifying which spot is the best fit. Entrepreneur selected 10 contemporary American lifestyles and 50 related cities to complement all kinds of business types. Whether you're looking for tropical breezes, crisp mountain air, crowded city streets or wide, open spaces, they're all here.

Our methodology is as far-ranging as the list itself, incorporating statistical data, lifestyle studies and empirical research. Some choices may seem to be no-brainers, others may surprise you, and still others may have you reconsidering segments of the U.S. in a whole new light. That's the essence of American business: The only constant is change.

Editor's Pick

Related Topics

Side Hustle

Anyone Can Start a Passive Income Side Hustle For Easy Money — But Only If You Know These 5 Essential Tips First.

The rise of digital automation technology has made starting a passive income side hustle easier and more accessible than ever before.

Side Hustle

He Launched His Creative Side Hustle Out of a Garage. Now It's Worth $225 Million.

Tom Humble, CXO and founder of E.C.D. Automotive Design, followed his passion for custom auto design into big business.

Business News

An Hermès Heir Wants to Give Half His $12 Billion Fortune to His Gardener—and Lawyers Are Going Nuts

Nicolas Puech, the grandson of Hermès' founder, intends to legally adopt the 51-year-old former groundskeeper as his son, ensuring he inherits his billions.

Business News

This Company Promised to Transform Drive-Thrus With AI — But the Secret Powering Its Tech? Humans.

Presto Automation Inc., one of several major players in AI-ordering tech, has made headlines for using off-site employees in places like the Phillippines.