This $100-a-Month Pill Can Extend the Life of Your Dog — Here’s What It Means for Pets and Humans

Loyal, a daily prescription pill targeting senior dogs, could add years to their lives. Is it also a proving ground for human longevity drugs?

By Jonathan Small | edited by Brittany Robins | May 04, 2026
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One of the hardest parts of loving a dog is knowing you’ll almost certainly outlive them. But a San Francisco startup is on its way to bringing the first dog longevity drug to market.

Loyal, founded by 31-year-old Celine Halioua, has developed LOY-002, a daily pill for senior dogs that targets the metabolic drivers of aging. The company has raised over $150 million and completed the largest clinical trial in veterinary medicine history — 1,300 dogs across 70 clinics — to prove the drug works. The FDA has already signed off on its safety and reasonable expectation of effectiveness, putting Loyal on track to launch as soon as next year for around $100 a month.

But Halioua’s ambitions extend beyond dog years. She also has her sights on humans. Federal approval for animal drugs takes years instead of decades, and dogs age quickly enough to show results. If a pill can safely add healthy years to a dog’s life, the leash to similar treatments for humans gets significantly shorter — and the $10 billion longevity industry gets its first FDA-approved proof of concept.

One of the hardest parts of loving a dog is knowing you’ll almost certainly outlive them. But a San Francisco startup is on its way to bringing the first dog longevity drug to market.

Loyal, founded by 31-year-old Celine Halioua, has developed LOY-002, a daily pill for senior dogs that targets the metabolic drivers of aging. The company has raised over $150 million and completed the largest clinical trial in veterinary medicine history — 1,300 dogs across 70 clinics — to prove the drug works. The FDA has already signed off on its safety and reasonable expectation of effectiveness, putting Loyal on track to launch as soon as next year for around $100 a month.

But Halioua’s ambitions extend beyond dog years. She also has her sights on humans. Federal approval for animal drugs takes years instead of decades, and dogs age quickly enough to show results. If a pill can safely add healthy years to a dog’s life, the leash to similar treatments for humans gets significantly shorter — and the $10 billion longevity industry gets its first FDA-approved proof of concept.

Jonathan Small Founder, Strike Fire Productions

Entrepreneur Staff
Jonathan Small is a bestselling author, journalist, producer, and podcast host. For 25 years, he... Read more
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