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Ryo Kubora performed nearly a thousand eye surgeries and discovered the gene that causes glaucoma, before starting his biotech company, Acucela. His innovation in the field of eye diseases makes him a finalist for Entrepreneur of 2012.

Retailers can learn about such opportunities from brokers, matchmaking services or simply word-of-mouth.

A Seattle couple makes the jump into franchising with iFly.

How do the big companies stay on top? Take a look at some of the new customer-service ideas Amazon, USPS and Starbucks have in store.

One Seattle organization provides back-office guidance and services to artists short on business savvy.

Producing and using locally sourced food is becoming a sustainable business. Call it Foodie Inc.

Want to take your recipes on the road? Here are the basics.

This Seattle bar can be a great place to power through emails.

This crash course for would-be entrepreneurs is hard-core.

I write a lot on this blog about how to keep your doors open — how to survive the downturn and make it through these tough times. Today, though, let’s take a longer view and talk about how to build your company for the long haul. Specifically, how can you design your business to last […]

Ace Hotel founder Alex Calderwood did it by transforming his company into a lifestyle brand. Meet the man who set a new industry standard with the 'it' hotel.

personal, half-hour chat with President Barack Obama Grand Central Bakery Tutta Bella Neapolitan Pizzeria Inn at Discovery Coast talking up his stalled small-business lending proposal $30 billion in new federal funds Main Street Alliance

When the coffee giant opened a 'stealth' outlet in its own hometown, it was the espresso shot heard around the world.

The King Of E-Commerce

The digital demagogue earned billions by anticipating the market's needs. Now, his philanthropic foundation is helping countless others across the globe.

Weight-Loss Franchises Pursue Fat Profits